ADASTRA v6.1.1
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rs2170577
chr4:176195758
G
>
T
Sequence
cgggtatcgagggaggcaaagctg[G/T]ggtcccagtggtgtggctgcggtc
ASB in cell types
K562 (myelogenous leukemia)
CAR-T cells
adult erythroblasts
ASB for transcription factors
IRF4_HUMAN
NRF1_HUMAN
KDM1A_HUMAN
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View in UCSC Genome Browser
View in PheLiGe
0.05
FDR threshold
0
ES threshold
Color scale
-log10 FDR of Ref (
G
) ASB
-log10 FDR of Alt (
T
) ASB
Details
Transcription factors
Cell types
Effect size Ref
(+6 others)
Selected columns
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Uniprot ID
Effect size Ref
Effect size Alt
FDR Ref
FDR Alt
Mean BAD
Motif fold change
Motif concordance
IRF4_HUMAN
-1.21
2.53
1.00
1.9·10
-7
1.00
n/a
No Hit
NRF1_HUMAN
-0.39
0.95
1.00
3.9·10
-5
2.00
n/a
No Hit
KDM1A_HUMAN
-0.50
2.92
0.92
2.2·10
-3
2.00
n/a
n/a
Items per page:
5
1 – 3 of 3
Motif analysis
No data available
Genetic associations
GRASP
advanced age-related macular degeneration
,
ldl cholesterol
,
serum creatinine
GTEx eQTL
Cells_EBV-transformed_lymphocytes
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Generated by ADASTRA database
2025.04.22 v6.1.1 Mabel
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SNP set annotation with ANANASTRA
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+/-100bp
log2-scale
log2(Alt/Ref motif p-value)