rs2585175 chr8:142699871 G>C

Sequence
actgctcaaaagaatgagtcagtc[G/C]ctactcacgctggggagaccctct
ASB in cell types
HEK293 (embryonic kidney) MDM(monocyte derived macrophages) HEK293T (embryonic kidney)
ASB for transcription factors
OSR2_HUMAN SPI1_HUMAN PRDM4_HUMAN ARNT_HUMAN
Search SNPs nearby
View in UCSC Genome Browser
View in PheLiGe

Color scale

color scale ref
-log10 FDR of Ref (G) ASB
color scale alt
-log10 FDR of Alt (C) ASB

Details

Uniprot ID
Effect size Ref
Effect size Alt
FDR Ref
FDR Alt
Mean BAD
Motif fold change
Motif concordance
OSR2_HUMAN 2.52 n/a 3.3·10-71.00 1.50 -1.88 Weak Concordant
SPI1_HUMAN 1.87 0.48 3.8·10-60.79 1.52 n/a No Hit
PRDM4_HUMAN 3.40 -3.08 9.7·10-61.00 1.00 n/a No Hit
ARNT_HUMAN 2.90 0.21 3.3·10-30.73 2.00 0.15 Weak Discordant
ZN843_HUMAN 2.58 -2.24 7.6·10-31.00 1.00 n/a n/a
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Motif analysis

ARNT_HUMAN Weak Discordant
ARNT_HUMAN pic

Genetic associations

GRASP aortic valve calcium,  college completion,  hdl cholesterol,  height,  years of education
GTEx eQTL Adipose_Subcutaneous,  Adipose_Visceral_Omentum,  Adrenal_Gland,  Artery_Aorta,  Artery_Coronary,  Artery_Tibial,  Brain_Amygdala,  Brain_Anterior_cingulate_cortex_BA24,  Brain_Caudate_basal_ganglia,  Brain_Cerebellar_Hemisphere,  Brain_Cerebellum,  Brain_Cortex,  Brain_Frontal_Cortex_BA9,  Brain_Hippocampus,  Brain_Hypothalamus,  Brain_Nucleus_accumbens_basal_ganglia,  Brain_Putamen_basal_ganglia,  Brain_Spinal_cord_cervical_c-1,  Brain_Substantia_nigra,  Breast_Mammary_Tissue,  Cells_Cultured_fibroblasts,  Colon_Sigmoid,  Colon_Transverse,  Esophagus_Gastroesophageal_Junction,  Esophagus_Mucosa,  Esophagus_Muscularis,  Heart_Atrial_Appendage,  Heart_Left_Ventricle,  Liver,  Lung,  Minor_Salivary_Gland,  Muscle_Skeletal,  Nerve_Tibial,  Ovary,  Pancreas,  Pituitary,  Prostate,  Skin_Not_Sun_Exposed_Suprapubic,  Skin_Sun_Exposed_Lower_leg,  Small_Intestine_Terminal_Ileum,  Spleen,  Stomach,  Testis,  Thyroid,  Uterus,  Whole_Blood

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