rs4387287 chr10:103918139 A>C

Sequence
ccgcctgcagctccaggagccctg[A/C]gacctggcccttccggcgctcgga
ASB in cell types
HepG2 (hepatoblastoma) primary B-CLL cells GM12878 (female B-cells lymphoblastoid cell line) CD14+ monocytes
ASB for transcription factors
BRD4_HUMAN RBM25_HUMAN STAT1_HUMAN FOXK2_HUMAN
Search SNPs nearby
View in UCSC Genome Browser
View in PheLiGe

Color scale

color scale ref
-log10 FDR of Ref (A) ASB
color scale alt
-log10 FDR of Alt (C) ASB

Details

Uniprot ID
Effect size Ref
Effect size Alt
FDR Ref
FDR Alt
Mean BAD
Motif fold change
Motif concordance
BRD4_HUMAN 1.21 2.74 0.281.4·10-4 1.57 n/a n/a
RBM25_HUMAN 0.26 3.14 0.743.5·10-4 1.00 n/a n/a
STAT1_HUMAN -1.47 2.63 1.007.8·10-4 2.00 n/a No Hit
FOXK2_HUMAN -0.23 2.84 0.852.2·10-3 1.00 n/a No Hit
GCR_HUMAN 0.99 1.49 1.002.2·10-3 1.00 n/a No Hit
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Motif analysis

ESR1_HUMAN Weak Concordant
ESR1_HUMAN pic

Genetic associations

EMBL-EBI diastolic blood pressure,  hypertension,  systolic blood pressure,  telomere length
GRASP advanced age-related macular degeneration (choroidal neovascularization) vs. no amd,  college completion,  diastolic blood pressure (dbp),  fasting insulin,  hdl cholesterol,  height,  homa-b,  homa-ir,  leukocyte telomere length,  parkinsons disease,  prop taste detection threshold,  systolic blood pressure (sbp)
GTEx eQTL Adipose_Subcutaneous,  Brain_Frontal_Cortex_BA9,  Cells_Cultured_fibroblasts,  Colon_Sigmoid,  Colon_Transverse,  Esophagus_Mucosa,  Esophagus_Muscularis,  Heart_Atrial_Appendage,  Heart_Left_Ventricle,  Lung,  Muscle_Skeletal,  Nerve_Tibial,  Skin_Not_Sun_Exposed_Suprapubic,  Skin_Sun_Exposed_Lower_leg,  Spleen

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