ADASTRA v6.1.0
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rs6675979
chr1:4007992
G
>
A
Sequence
ttataacctaatctcagaggtgac[G/A]tcacccttttgccagatgatcaca
ASB in cell types
K562 (myelogenous leukemia)
germinal center B-cells
ASB for transcription factors
ATF7_HUMAN
ATF3_HUMAN
ATF2_HUMAN
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View in UCSC Genome Browser
View in PheLiGe
0.05
FDR threshold
0
ES threshold
Color scale
-log10 FDR of Ref (
G
) ASB
-log10 FDR of Alt (
A
) ASB
Details
Transcription factors
Cell types
Effect size Ref
(+6 others)
Selected columns
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Uniprot ID
Effect size Ref
Effect size Alt
FDR Ref
FDR Alt
Mean BAD
Motif fold change
Motif concordance
ATF7_HUMAN
2.08
-1.84
3.9·10
-4
1.00
1.25
-1.49
Weak Concordant
ATF3_HUMAN
2.61
-2.37
5.8·10
-3
1.00
2.50
-0.57
Weak Concordant
ATF2_HUMAN
2.63
-5.27
0.01
1.00
3.00
1.02
Weak Discordant
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5
1 – 3 of 3
Motif analysis
ATF2_HUMAN
Weak Discordant
Show reverse complement
Show rev. comp.
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ATF3_HUMAN
Weak Concordant
ATF7_HUMAN
Weak Concordant
Genetic associations
GRASP
advanced age-related macular degeneration
,
ldl cholesterol
,
total cholesterol
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Generated by ADASTRA database
2024.11.16 v6.1.0 Mabel
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SNP set annotation with ANANASTRA
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+/-100bp
log2-scale
log2(Alt/Ref motif p-value)
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