rs805305 chr6:31729610 C>G

Sequence
cgcagggactggaagtccagcccg[C/G]gacccgcaggggttatgggacaga
ASB in cell types
K562 (myelogenous leukemia) HepG2 (hepatoblastoma) 2588 (Lymphoblastoid Cell Lines) GM12878 (female B-cells lymphoblastoid cell line)
ASB for transcription factors
VEZF1_HUMAN KLF13_HUMAN STAG1_HUMAN ZF64B_HUMAN
Search SNPs nearby
View in UCSC Genome Browser
View in PheLiGe

Color scale

color scale ref
-log10 FDR of Ref (C) ASB
color scale alt
-log10 FDR of Alt (G) ASB

Details

Uniprot ID
Effect size Ref
Effect size Alt
FDR Ref
FDR Alt
Mean BAD
Motif fold change
Motif concordance
VEZF1_HUMAN n/a 2.99 1.006.1·10-4 3.00 n/a No Hit
KLF13_HUMAN n/a 1.48 1.003.1·10-3 3.00 n/a No Hit
STAG1_HUMAN 0.59 0.30 8.3·10-31.00 1.00 n/a n/a
ZF64B_HUMAN -4.94 2.87 1.009.4·10-3 2.00 5.69 Concordant
SNAI2_HUMAN 2.38 -1.98 0.021.00 1.50 n/a No Hit
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Motif analysis

ZF64B_HUMAN Concordant
ZF64B_HUMAN pic

Genetic associations

GRASP chronic kidney disease,  diabetic retinopathy in type 2 diabetes mellitus,  diastolic blood pressure (dbp),  hdl cholesterol,  microalbuminuria,  rheumatoid arthritis,  serum creatinine,  systolic blood pressure (sbp),  triglycerides change with statins
GTEx eQTL Adipose_Subcutaneous,  Adipose_Visceral_Omentum,  Adrenal_Gland,  Artery_Aorta,  Artery_Coronary,  Artery_Tibial,  Brain_Amygdala,  Brain_Anterior_cingulate_cortex_BA24,  Brain_Caudate_basal_ganglia,  Brain_Cerebellar_Hemisphere,  Brain_Cerebellum,  Brain_Cortex,  Brain_Frontal_Cortex_BA9,  Brain_Hippocampus,  Brain_Hypothalamus,  Brain_Nucleus_accumbens_basal_ganglia,  Brain_Putamen_basal_ganglia,  Brain_Spinal_cord_cervical_c-1,  Breast_Mammary_Tissue,  Cells_Cultured_fibroblasts,  Cells_EBV-transformed_lymphocytes,  Colon_Sigmoid,  Colon_Transverse,  Esophagus_Gastroesophageal_Junction,  Esophagus_Mucosa,  Esophagus_Muscularis,  Heart_Atrial_Appendage,  Heart_Left_Ventricle,  Liver,  Lung,  Minor_Salivary_Gland,  Muscle_Skeletal,  Nerve_Tibial,  Pancreas,  Pituitary,  Prostate,  Skin_Not_Sun_Exposed_Suprapubic,  Skin_Sun_Exposed_Lower_leg,  Small_Intestine_Terminal_Ileum,  Spleen,  Stomach,  Testis,  Thyroid,  Vagina,  Whole_Blood

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