rs10899314 chr11:76920254 T>A

Sequence
aacgtggctgtcagcagcacctag[T/A]ggtcagtagcatcccctgcccacc
ASB in cell types
A549 (lung carcinoma) GM17942 (lymphoblastoid cell) SH-SY5Y (neuroblastoma) glioblastoma cells
ASB for transcription factors
CTCF_HUMAN RAD21_HUMAN SMC3_HUMAN STAG1_HUMAN
Search SNPs nearby
View in UCSC Genome Browser
View in PheLiGe

Color scale

color scale ref
-log10 FDR of Ref (T) ASB
color scale alt
-log10 FDR of Alt (A) ASB

Details

Uniprot ID
Effect size Ref
Effect size Alt
FDR Ref
FDR Alt
Mean BAD
Motif fold change
Motif concordance
CTCF_HUMAN 2.12 0.25 1.5·10-1271.00 1.51 -2.81 Concordant
RAD21_HUMAN 1.53 0.02 3.9·10-51.00 1.83 n/a n/a
SMC3_HUMAN 1.46 -0.39 2.1·10-41.00 1.94 n/a n/a
STAG1_HUMAN 0.76 -0.97 5.7·10-31.00 1.38 n/a n/a
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Motif analysis

CTCF_HUMAN Concordant
CTCF_HUMAN pic

Genetic associations

GRASP advanced age-related macular degeneration (geographic atrophy),  ldl cholesterol change with statins,  serum creatinine,  total cholesterol change with statins
GTEx eQTL Colon_Transverse,  Esophagus_Mucosa,  Nerve_Tibial,  Skin_Sun_Exposed_Lower_leg,  Small_Intestine_Terminal_Ileum,  Spleen,  Stomach,  Testis

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