rs6681671 chr1:114758064 C>T

Sequence
gggcggagtgaagcgtactctcaa[C/T]acgcttgcgcagcagggctaagtg
ASB in cell types
MCF7 (Invasive ductal breast carcinoma) K562 (myelogenous leukemia) MCF7L-P(immortalized breast epithelial cell line) CD14+ monocytes
ASB for transcription factors
FOXA1_HUMAN NELFE_HUMAN NRF1_HUMAN STAT1_HUMAN
Search SNPs nearby
View in UCSC Genome Browser
View in PheLiGe

Color scale

color scale ref
-log10 FDR of Ref (C) ASB
color scale alt
-log10 FDR of Alt (T) ASB

Details

Uniprot ID
Effect size Ref
Effect size Alt
FDR Ref
FDR Alt
Mean BAD
Motif fold change
Motif concordance
FOXA1_HUMAN 0.19 2.69 1.007.4·10-17 2.50 n/a No Hit
NELFE_HUMAN -0.35 1.87 1.001.0·10-10 3.62 n/a n/a
NRF1_HUMAN -0.11 2.92 1.003.0·10-10 1.85 2.71 Concordant
STAT1_HUMAN 1.90 0.24 8.3·10-51.00 1.75 n/a No Hit
MEIS2_HUMAN -1.33 1.33 1.005.1·10-4 1.00 n/a No Hit
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Motif analysis

NRF1_HUMAN Concordant
NRF1_HUMAN pic

Genetic associations

GRASP fasting insulin,  homa-b,  homa-ir,  urinary albumin-to-creatinine ratio
GTEx eQTL Artery_Tibial,  Esophagus_Muscularis,  Muscle_Skeletal,  Skin_Not_Sun_Exposed_Suprapubic,  Skin_Sun_Exposed_Lower_leg

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