ADASTRA v1.6.10
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rs137115
chr22:42615397
T
>
C
Sequence
ctgggagttgcgatctgcccgacc[T/C]tattcacgcctaaaaagtagactg
ASB in cell types
HEK293 (embryonic kidney)
monocyte-derived macrophages
germinal center B-cells
cranial neural crest cells
ASB for transcription factors
BCL6_HUMAN
STAT1_HUMAN
TF65_HUMAN
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Color scale
-log10 FDR of Ref (
T
) ASB
-log10 FDR of Alt (
C
) ASB
Details
Transcription factors
Cell types
Effect size Ref
(+6 others)
Selected columns
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Uniprot ID
Effect size Ref
Effect size Alt
FDR Ref
FDR Alt
Mean BAD
Motif fold change
Motif concordance
BCL6_HUMAN
-0.66
2.15
0.86
6.5·10
-3
2.25
n/a
No Hit
STAT1_HUMAN
-0.08
1.83
1.00
7.1·10
-3
2.20
n/a
No Hit
TF65_HUMAN
0.85
2.51
0.34
9.6·10
-3
1.61
n/a
No Hit
Items per page:
5
1 – 3 of 3
Motif analysis
No data available
Genetic associations
EMBL-EBI
parental extreme longevity (95 years and older)
GRASP
refractive error
GTEx eQTL
Adipose_Subcutaneous
,
Breast_Mammary_Tissue
,
Cells_Cultured_fibroblasts
,
Colon_Sigmoid
,
Lung
,
Nerve_Tibial
,
Skin_Sun_Exposed_Lower_leg
,
Thyroid
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Generated by ADASTRA database
2020.06.22 v1.6.10 Soos
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SNP set annotation with ANANASTRA
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+/-100bp
log2-scale
log2(Alt/Ref motif p-value)