rs2954658 chr8:144792397 C>T
- Sequence
ccagcgcggccgaaagaggaaaca[C/T]ggcgtcagcgagcggccttatctt
- ASB in cell types
- K562 (myelogenous leukemia) HEK293T (embryonic kidney) HCT-116 (colon carcinoma) MDA-MB-453 (breast adenocarcinoma)
- ASB for transcription factors
- TYY1_HUMAN MYC_HUMAN KDM1A_HUMAN GABP1_HUMAN
View in PheLiGe Color scale
-log10 FDR of Ref (C) ASB
-log10 FDR of Alt (T) ASB
Details
Transcription factors
Cell types
Uniprot ID | Effect size Ref | Effect size Alt | FDR Ref | FDR Alt | Mean BAD | Motif fold change | Motif concordance | |
|---|---|---|---|---|---|---|---|---|
| TYY1_HUMAN | -1.36 | 2.19 | 1.44 | 5.35 | Concordant | |||
| MYC_HUMAN | -0.10 | 1.75 | 1.78 | n/a | No Hit | |||
| KDM1A_HUMAN | 1.81 | -1.46 | 2.00 | n/a | n/a | |||
| GABP1_HUMAN | 0.29 | -1.33 | 1.67 | n/a | n/a | |||
| FLI1_HUMAN | -0.06 | 1.81 | 1.88 | -0.32 | Weak Discordant |
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Motif analysis
Genetic associations
GTEx eQTL Adipose_Subcutaneous, Adipose_Visceral_Omentum, Adrenal_Gland, Artery_Aorta, Artery_Coronary, Artery_Tibial, Brain_Anterior_cingulate_cortex_BA24, Brain_Caudate_basal_ganglia, Brain_Cerebellar_Hemisphere, Brain_Cerebellum, Brain_Cortex, Brain_Frontal_Cortex_BA9, Brain_Hippocampus, Brain_Hypothalamus, Brain_Nucleus_accumbens_basal_ganglia, Brain_Putamen_basal_ganglia, Breast_Mammary_Tissue, Cells_Cultured_fibroblasts, Cells_EBV-transformed_lymphocytes, Colon_Sigmoid, Colon_Transverse, Esophagus_Gastroesophageal_Junction, Esophagus_Mucosa, Esophagus_Muscularis, Heart_Atrial_Appendage, Heart_Left_Ventricle, Liver, Lung, Minor_Salivary_Gland, Muscle_Skeletal, Nerve_Tibial, Ovary, Pancreas, Pituitary, Prostate, Skin_Not_Sun_Exposed_Suprapubic, Skin_Sun_Exposed_Lower_leg, Small_Intestine_Terminal_Ileum, Spleen, Stomach, Testis, Thyroid, Uterus, Vagina, Whole_Blood