ADASTRA v1.6.10
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Soos
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rs312172
chr12:104740843
A
>
G
Sequence
cctaagaagccgcagagatgtctg[A/G]cttcctcagtgaacagcagatgga
ASB in cell types
monocyte-derived dendritic cells
periferal blood macrophages
CD14+ monocytes
GM12891 (male B-cells)
ASB for transcription factors
SPI1_HUMAN
STAT1_HUMAN
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View in PheLiGe
Color scale
-log10 FDR of Ref (
A
) ASB
-log10 FDR of Alt (
G
) ASB
Details
Transcription factors
Cell types
Effect size Ref
(+6 others)
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Uniprot ID
Effect size Ref
Effect size Alt
FDR Ref
FDR Alt
Mean BAD
Motif fold change
Motif concordance
SPI1_HUMAN
2.23
-1.42
3.6·10
-10
1.00
1.93
-2.43
Concordant
STAT1_HUMAN
1.85
n/a
1.5·10
-3
1.00
2.50
n/a
No Hit
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Motif analysis
SPI1_HUMAN
Concordant
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Genetic associations
GRASP
hypertension (early onset hypertension)
,
tetrology of fallot
,
total cholesterol change with statins
GTEx eQTL
Artery_Aorta
,
Artery_Tibial
,
Esophagus_Muscularis
,
Testis
,
Thyroid
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Generated by ADASTRA database
2020.06.22 v1.6.10 Soos
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SNP set annotation with ANANASTRA
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+/-100bp
log2-scale
log2(Alt/Ref motif p-value)
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