rs410867 - ADASTRA v1.6.10

rs410867 chr19:16316300 A>G

Sequence: acatactgaaaaagggttgtgcaa[A/G]cttcagcagaaacaccccaattgc
ASB in cell types: K562 (myelogenous leukemia) fetal bone marrow-derived mononuclear cells
ASB for transcription factors: CEBPB_HUMAN TIF1A_HUMAN ATF3_HUMAN ATF4_HUMAN
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Color scale

-log10 FDR of Ref (A) ASB

-log10 FDR of Alt (G) ASB

Details

Transcription factors

Cell types

Uniprot ID	Effect size Ref	Effect size Alt	FDR Ref	FDR Alt	Mean BAD	Motif fold change	Motif concordance
CEBPB_HUMAN	0.29	1.17	1.00	9.2·10^-8	1.73	4.89	Concordant
TIF1A_HUMAN	n/a	2.57	1.00	1.2·10^-5	2.00	n/a	n/a
ATF3_HUMAN	n/a	2.49	1.00	7.8·10^-5	2.00	n/a	No Hit
ATF4_HUMAN	n/a	2.72	1.00	7.0·10^-4	2.00	n/a	No Hit
KDM1A_HUMAN	-2.17	2.32	1.00	4.3·10^-3	2.00	n/a	n/a

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Motif analysis

CEBPB_HUMAN

Concordant

Genetic associations

EMBL-EBI eosinophil counts, eosinophil percentage of granulocytes, eosinophil percentage of white cells, neutrophil percentage of granulocytes, sum eosinophil basophil counts

GRASP height, ldl cholesterol, parkinsons disease, rheumatoid arthritis