ADASTRA v1.6.10
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rs588568
chr19:55587480
C
>
G
Sequence
tttccagtgcgcagctccggggct[C/G]agcctgtctctaagccggtctcgg
ASB in cell types
K562 (myelogenous leukemia)
MCF7 (Invasive ductal breast carcinoma)
GM12878 (female B-cells)
ASB for transcription factors
FOXK2_HUMAN
NFIB_HUMAN
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Color scale
-log10 FDR of Ref (
C
) ASB
-log10 FDR of Alt (
G
) ASB
Details
Transcription factors
Cell types
Effect size Ref
(+6 others)
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Uniprot ID
Effect size Ref
Effect size Alt
FDR Ref
FDR Alt
Mean BAD
Motif fold change
Motif concordance
FOXK2_HUMAN
-0.67
1.73
1.00
2.2·10
-3
1.78
n/a
n/a
NFIB_HUMAN
-2.80
2.24
1.00
0.01
3.00
n/a
n/a
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5
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Motif analysis
No data available
Genetic associations
GRASP
advanced age-related macular degeneration (geographic atrophy)
,
serum creatinine
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Generated by ADASTRA database
2020.06.22 v1.6.10 Soos
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SNP set annotation with ANANASTRA
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+/-100bp
log2-scale
log2(Alt/Ref motif p-value)