ASB stands for
Allele-
Specific
Binding. A
Transcription
Factor (
TF) might prefer to bind one of two alternative alleles of homologous chromosomes and thus exhibit allele-specific binding. ASB highlights regulatory SNPs with high potential to affect gene expression. Systematic dissection of ChIP-Seq data processed in the
GTRD database allowed us to identify hundreds of thousands ASB events for a wide range of transcription factors.